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KMID : 0882420150890010122
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Korean Journal of Medicine
2015 Volume.89 No. 1 p.122 ~ p.126
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A Case of Rheumatoid Arthritis Accompanied by Thrombotic Thrombocytopenic Purpura
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Kang Sung-Min
Lee Ji-Hyun
Ku In-Hye
Kim Hae-Koo
Nam Kyoung-Sik
Park Suk-Ki
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Abstract
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Thrombotic thrombocytopenic purpura (TTP) is a blood coagulation disorder that damages numerous organs, including the kidney, heart and brain. Features indicative of TTP include thrombocytopenia, microangiopathic hemolytic anemia, neurologic symptoms, kidney failure and fever. Infections, toxins, pregnancy and, rarely, autoimmune diseases are all known to be associated with TTP. We encountered a rare case of rheumatoid arthritis accompanied by TTP following tympanoplasty. The patient’s confusion, thrombocytopenia and renal failure all improved after plasmapheresis and high-dose glucocorticoid therapy, but she eventually expired due to sepsis. We report on this case herein and also review the relevant literature.
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KEYWORD
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Thrombotic thrombocytopenic purpura, Rheumatoid arthtiris, Plasmapheresis
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